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1.
Actas Urol Esp ; 33(4): 390-401, 2009 Apr.
Artigo em Espanhol | MEDLINE | ID: mdl-19579890

RESUMO

INTRODUCTION: The DHEA widely used for the control of the symptoms associated with the aging, has been an object of numerous clinical essays with discordant results as for its efficiency. OBJECTIVES: The present review tries to analyze the existing information by means of a search and systematic review of articles centred on the utilization of the DHEA/S for the control of the aging symptoms. MATERIAL AND METHODS: Systematic review of the literature and application of the skills of metaanalisis to value the efficiency of the DHEA/S, for it settles down the process of prospective form, 152 articles were checked and 25 were in use for adding only their results. RESULTS: Since the only (unique) prominent information seems to concern the metabolism of the carbohydrates increasing the efficiency of the insulin. CONCLUSIONS: The studies do not sustain the usefulness of the DHEA for the reduction of the symptoms associated with the aging.


Assuntos
Desidroepiandrosterona/uso terapêutico , Libido/efeitos dos fármacos , Envelhecimento , Feminino , Humanos , Masculino , Pessoa de Meia-Idade
2.
Actas urol. esp ; 33(4): 390-401, abr. 2009. tab
Artigo em Espanhol | IBECS | ID: ibc-60053

RESUMO

Introducción: La Dehidroepiandrosterona, ampliamente utilizada para el control de los síntomas asociados al envejecimiento, ha sido objeto de numerosos ensayos clínicos con resultados discordantes en cuanto a su eficacia. Objetivos: La presente revisión pretende analizar la información existente mediante una búsqueda y revisión sistemática de artículos centrados en la utilización de la DHEA/S para el control de los síntomas del envejecimiento. Material y métodos: Revisión sistemática de la literatura y aplicación de las técnicas de metaánalisis para valorar la eficacia de la DHEA/S, para ello se normaliza el proceso de forma prospectiva, se revisaron 152 artículos y se utilizaron únicamente 25 para agregar sus resultados. Resultados: Como único dato destacable, parece afectar al metabolismo de los hidratos de carbono aumentando la eficacia de la insulina. Conclusión: Los estudios no sustentan la utilidad de la DHEA para la reducción de los síntomas asociados al envejecimiento (AU)


Introduction: The DHEA widely used for the control of the symptoms associated with the aging, has been an object of numerous clinical essays with discordant results as for its efficiency. Objectives: The present review tries to analyze the existing information by means of a search and systematic review of articles centred on the utilization of the DHEA/S for the control of the aging symptoms. Material and methods: Systematic review of the literature and application of the skills of metaanalisis to value the efficiency of the DHEA/S, for it settles down the process of prospective form, 152 articles were checked and 25 were in use for adding only their results. Results: Since the only (unique) prominent information seems to concern the metabolism of the carbohydrates increasing the efficiency of the insulin. Conclusions: The studies do not sustain the usefulness of the DHEA for the reduction of the symptoms associated with the aging (AU)


Assuntos
Humanos , Masculino , Feminino , Pessoa de Meia-Idade , Desidroepiandrosterona/farmacologia , Desidroepiandrosterona/uso terapêutico , Libido/fisiologia , Envelhecimento/fisiologia , Metanálise como Assunto , Metabolismo dos Carboidratos , Insulina
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